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Year : 2022  |  Volume : 37  |  Issue : 2  |  Page : 50-54

To evaluate the efficacy of antibiotic-coated intramedullary locking nail in the compound fracture of tibia

1 Department of Orthopaedics, S.N. Medical College, Agra, Uttar Pradesh, India
2 Department of Orthopaedics, M.L.N. Medical College, Prayagraj, Uttar Pradesh, India

Correspondence Address:
Shailesh Kumar
Department of Orthopaedics, M.L.N. Medical College, Prayagraj, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jbjd.jbjd_17_22

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Introduction: Soft tissue with skeletal infections remains a big problem for orthopaedic surgeons. Bone provides a unique milieu for bacteria, with low vascularity and turnover rate. Biofilm-forming bacteria cause most orthopaedic trauma infections. When biofilm is formed, it protects the microorganism from antimicrobial treatment thus leading to chronic infections. Antibiotic-coated interlocking nail locally releases gentamycin + PDLLA at initial high concentrations followed by a period of constant release. The biodegradable polymer (PDLLA) is excreted from the body through the tricorboxylic acid cycle cycle, combined with gentamycin for sustained release. Materials and Methods: This was a prospective interventional study conducted between September 2018 and August 2020. In this period, we analyzed the hospital records to find out the cases treated by antibiotic-coated intramedullary locking nails. A total of 30 cases of compound tibia fracture were included in our study. Patients were routinely followed at definite intervals and specifically assessed for radiographic and functional evaluation by using the RUST score. Results: Out of 30 patients, radiological union at 6 months using the RUST score was 4 in 10.00% patients, 8 in 13.33% patients, 10 in 23.33% patients and 12 in 53.33% patients and final functional outcome was “excellent” in 53.33% patients, “good” in 23.33% patients, “fair” in13.33 % patients and “poor” in 10.00% patients. Conclusion: Antibiotic-coated tibia interlocking nail yields good functional outcomes with fewer complications in these fractures. Antibiotic tibia interlocking nail is a good treatment option and should be used whenever indicated.

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